More Sensitive MRI Techniques for Detecting Focal Cortical Dysplasia
نویسندگان
چکیده
منابع مشابه
Towards in vivo focal cortical dysplasia phenotyping using quantitative MRI
Focal cortical dysplasias (FCDs) are a range of malformations of cortical development each with specific histopathological features. Conventional radiological assessment of standard structural MRI is useful for the localization of lesions but is unable to accurately predict the histopathological features. Quantitative MRI offers the possibility to probe tissue biophysical properties in vivo and...
متن کاملAutomatic Delineation of Focal Cortical Dysplasia Lesions on MRI
Rationale: MRI has allowed the recognition of focal cortical dysplasia (FCD) in an increasing number of patients. The precise delineation of FCD is important since freedom from seizures after surgery is closely related to the extent of resection of the pathological tissue. FCD lesions are difficult to delineate on MRI due to their ill-defined boundaries and the complexity of the cortex. We prev...
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Focal cortical dysplasia is a malformation of cortical development, which is the most common cause of medically refractory epilepsy in the pediatric population and the second/third most common etiology of medically intractable seizures in adults.Both genetic and acquired factors are involved in the pathogenesis of cortical dysplasia. Numerous classifications of the complex structural abnormalit...
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Focal cortical dysplasias are common malformations of cerebral cortical development and are highly associated with medically intractable epilepsy. They have been classified into neuropathological subtypes (type Ia, Ib, IIa, IIb, and III) based on the severity of cytoarchitectural disruption--tangential or radial dispersion, or loss of laminar structure--and the presence of unique cells types su...
متن کاملCortical development and focal cortical dysplasia.
A brief survey of cortical development is presented, focusing on neuronal migration and its alterations. Corticogenesis is achieved through ordered temporospatial steps, via the formation of transient structures, and successive waves of cell proliferation and migration (followed by cell differentiation and maturation), and apoptotic cell death. The appearance of the proliferative ventricular zo...
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ژورنال
عنوان ژورنال: Epilepsy Currents
سال: 2003
ISSN: 1535-7597,1535-7511
DOI: 10.1046/j.1535-7597.2003.03112.x